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patA [2019-07-31 14:07:26]
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patA [2019-07-31 14:07:26]

N-acetyl-L,L-diaminopimelate aminotransferase
Locus
BSU_14000
Isoelectric point
6.01
Molecular weight
43.29 kDa
Protein length
393 aa Sequence Blast
Gene length
1182 bp Sequence Blast
Function
biosynthesis of lysine and peptidoglycan
Product
aminotransferase
Essential
yes
E.C.
2.6.1.-
Synonyms
uat,dapX
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Cell envelope and cell division → Cell wall synthesis → Biosynthesis of peptidoglycan
  • Metabolism → Amino acid/ nitrogen metabolism → Biosynthesis/ acquisition of amino acids → Biosynthesis/ acquisition of lysine/ threonine
  • Metabolism → Additional metabolic pathways → Biosynthesis of cell wall components → Biosynthesis of peptidoglycan
  • Groups of genes → Essential genes

    • Gene

    Coordinates
    1,471,857 1,473,038

    Phenotypes of a mutant

  • essential PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • N-acetyl-2-amino-6-ketopimelate - N-acetyl-L,L-2,6-diaminopimelate PubMed

    • Protein family

  • class-I pyridoxal-phosphate-dependent aminotransferase family (according to UniProt)

    • Paralogous protein(s)

  • AlaT, AspB

    • Cofactors

  • PLP

    • Structure

  • 1GDE (from Pyrococcus sp., 42% identity) PubMed

    • Localization

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    patA
    Description
    PubMed
    view in new tab

    Genes
    ykzT-patA
    Description
    PubMed
    view in new tab

    Biological materials

    Mutant

  • BKE14000 (patA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATAATTCATCACCTTAACA, downstream forward: _UP4_AACAACGGCGTTTAAGCCGT

    • References

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