membrane protein, required for SdpC toxin maturation
function
maturation of the SdpC toxin
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|toxins, antitoxins and immunity against toxins], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|AbrB regulon], [SW|Rok regulon], [SW|Spo0A regulon]Gene
Coordinates on the chromosome (coding sequence)
3,464,762 -> 3,465,733
The protein
[SW|Localization]
cell membrane [Pubmed|18763711]Expression and Regulation
Operon
''[protein|search|sdpA]-[protein|search|sdpB]-[protein|search|sdpC]'' [Pubmed|12817086]Regulation
expressed under conditions that trigger sporulation ([SW|Spo0A]) [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647,15687200 PubMed]repressed by [protein|search|Rok] [Pubmed|15743949]repressed during logrithmic growth ([protein|search|AbrB]) [http://www.ncbi.nlm.nih.gov/sites/entrez/15687200,17720793 PubMed]strongly repressed in response to glucose starvation in M9 medium [Pubmed|23033921]Regulatory mechanism
[SW|Spo0A]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647,15687200 PubMed][protein|search|Rok]: transcription repression [Pubmed|15743949][protein|search|AbrB]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/15687200,17720793 PubMed]Additional information
the amount of the mRNA is substantially decreased upon depletion of [Rny|search|RNase Y] [PubMed|21815947]References
Reviews
Original Publications
12817086,14651647,15687200,15743949,15687200,17720793,18763711,23687264,21815947,23033921 
