sdpB

membrane protein, required for SdpC toxin maturation

Locus: BSU_33760

Isoelectric point: 9.52

Molecular weight: 37.30 kDa

Protein length: 323 aa

Gene length: 972 bp

Function: maturation of the SdpC toxin

Product: unknown

Essential: no

Synonyms: yvaX

Genomic Context

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Categories containing this gene/protein

• Lifestyles → Coping with stress → Toxins, antitoxins and immunity against toxins
• Groups of genes → Membrane proteins

Gene

Coordinates: 3,464,762 3,465,733

The protein

Paralogous protein(s)

• YitO

Localization

• cell membrane PubMed

Expression and Regulation

Operons

• Genes: sdpA-sdpB-sdpC
  Description: PubMed

  Regulatory mechanism

  • Spo0A: activation, PubMed, in Spo0A regulon
  • Rok: repression, PubMed, in Rok regulon
  • AbrB: repression, PubMed, in AbrB regulon

  Regulation

  • expressed under conditions that trigger sporulation (Spo0A) PubMed

  Additional information

  • the amount of the mRNA is substantially decreased upon depletion of RNase Y PubMed

Biological materials

Mutant

• MGNA-A449 (yvaX::erm), available at the NBRP B. subtilis, Japan
• BKE33760 (sdpB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CTTCATACTATTTTTATTTT, downstream forward: _UP4_TAACATTTAGATAATGGAGA
• BKK33760 (sdpB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CTTCATACTATTTTTATTTT, downstream forward: _UP4_TAACATTTAGATAATGGAGA

References

Reviews

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Original Publications

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