fmt [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]

methionyl-tRNA formyltransferase

locus: BSU15730

pI: 5.62

mw: 34.00 kDa

function: formylation of Met-tRNA(fMet)

product: methionyl-tRNA formyltransferase

essential: yes

ec: 2.1.2.9

synonyms: yloL

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.8|tRNA modification and maturation]
• [category|SW 6|Groups of genes] → [category|SW 6.11|Efp-dependent proteins]

syns: yloL

[SW|Categories] containing this gene/protein

• [SW|translation], [SW|essential genes]

This gene is a member of the following [SW|regulons]

• [SW|Efp-dependent proteins]

Gene

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

Catalyzed reaction/ biological activity

• 10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) + H₂O = tetrahydrofolate + N-formylmethionyl-tRNA(fMet) (according to Swiss-Prot)

Protein family

• fmt family (according to Swiss-Prot)

Structure

• [PDB|3RFO] (from ''Bacillus anthracis'', 69% identity, 89% similarity)

Expression and Regulation

Operon

• ''[protein|search|defA]-[protein|search|fmt]-[protein|search|yloM]'' [Pubmed|16964327]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|16964327]

References

• 8887566,19171795