SubtiBank SubtiBank
fmt [Mon Aug 31 2015 13:54:15 GMT+0200 (CEST)]
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fmt [Mon Aug 31 2015 13:54:15 GMT+0200 (CEST)]

methionyl-tRNA formyltransferase
Locus
BSU15730
Isoelectric point
5.00
Molecular weight
34.00 kDa
Function
formylation of Met-tRNA(fMet)
Product
methionyl-tRNA formyltransferase
Essential
yes
E.C.
2.1.2.9
Synonyms
yloL
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Protein synthesis, modification and degradation → Translation → tRNA modification and maturation
  • Groups of genes → Efp-dependent proteins

    • Categories containing this gene/protein

  • translation, essential genes

    • This gene is a member of the following regulons

  • Efp-dependent proteins

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,646,999 -> 1,647,952

    Phenotypes of a mutant

  • essential PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • 10-formyltetrahydrofolate L-methionyl-tRNA(fMet) H2O = tetrahydrofolate N-formylmethionyl-tRNA(fMet) (according to Swiss-Prot)

    • Protein family

  • fmt family (according to Swiss-Prot)

    • Structure

  • 3RFO (from Bacillus anthracis, 69% identity, 89% similarity)

    • Expression and Regulation

    Operon

  • defA-fmt-yloM PubMed

    • Sigma factor

  • SigA PubMed

    • Additional information

  • translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

    • References

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