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fmt [Mon Aug 31 2015 13:54:15 GMT+0200 (CEST)]
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fmt [Mon Aug 31 2015 13:54:15 GMT+0200 (CEST)]

methionyl-tRNA formyltransferase
locus
BSU15730
pI
5.00
mw
34.00 kDa
function
formylation of Met-tRNA(fMet)
product
methionyl-tRNA formyltransferase
essential
yes
ec
2.1.2.9
synonyms
yloL
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.8|tRNA modification and maturation]
  • [category|SW 6|Groups of genes] → [category|SW 6.11|Efp-dependent proteins]

    • [SW|Categories] containing this gene/protein

  • [SW|translation], [SW|essential genes]

    • This gene is a member of the following [SW|regulons]

  • [SW|Efp-dependent proteins]

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,646,999 -> 1,647,952

    Phenotypes of a mutant

  • essential [Pubmed|12682299]

    • The protein

    Catalyzed reaction/ biological activity

  • 10-formyltetrahydrofolate L-methionyl-tRNA(fMet) H2O = tetrahydrofolate N-formylmethionyl-tRNA(fMet) (according to Swiss-Prot)

    • Protein family

  • fmt family (according to Swiss-Prot)

    • Structure

  • [PDB|3RFO] (from ''Bacillus anthracis'', 69% identity, 89% similarity)

    • Expression and Regulation

    Operon

  • ''[protein|search|defA]-[protein|search|fmt]-[protein|search|yloM]'' [Pubmed|16964327]

    • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|16964327]

    • Additional information

  • [protein|search|translation] is likely to require [protein|search|Efp] due to the presence of several consecutive proline residues [PubMed|23239624,23239623]

    • References

  • 8887566,19171795