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lipC [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]
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lipC [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]

spore coat protein, phospholipase implicated in spore germination
locus
BSU04110
pI
5.00
mw
23.00 kDa
function
spore germination
product
spore coat phospholipase B
essential
no
synonyms
ycsK

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.1|Utilization of lipids] → [category|SW 2.4.1.1|Utilization of phospholipids]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.5|Class V]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.4|Germination] → [category|SW 4.2.4.2|Additional germination proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|utilization of lipids], [SW|sporulation proteins], [SW|germination]
  • This gene is a member of the following [SW|regulons]

  • [SW|KipR regulon], [SW|SigK regulon], [SW|TnrA regulon], [SW|GerE regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    462,431 -> 463,072

    Phenotypes of a mutant

  • defective in L-alanine-stimulated germination [Pubmed|20057119]
  • The protein

    Catalyzed reaction/ biological activity

  • cleaves the fatty acids at the sn-1 and sn-2 positions of phospholipids [Pubmed|20057119]
  • Protein family

  • 'GDSL' lipolytic enzyme family (according to Swiss-Prot)
  • [SW|Localization]

  • spore coat (basement), localization depends on [SW|SpoIVA] [Pubmed|22171814,17220230,20057119]
  • Expression and Regulation

    Operon

  • ''[protein|search|ycsF]-[protein|search|ycsG]-[protein|search|ycsI]-[protein|search|kipI]-[protein|search|kipA]-[protein|search|kipR]-[protein|search|lipC]'' [Pubmed|9334321]
  • ''lipC'' (according to [http://dbtbs.hgc.jp/COG/prom/ycsFGI-kipIAR-ycsK.html DBTBS])
  • [SW|Sigma factor]

  • ''lipC'': [protein|search|SigK] [Pubmed|15699190,17220230]
  • Regulation

  • ''lipC'': expressed four hours after onset of sporulation ([protein|search|GerE]) [Pubmed|17220230]
  • Regulatory mechanism

  • ''[protein|search|ycsF]'': [protein|search|KipR]: transcription repression [Pubmed|9334321]
  • ''[protein|search|ycsF]'': [protein|search|TnrA]: transcription activation [Pubmed|9334321]
  • [protein|search|GerE]: transcription activation [Pubmed|17220230]
  • References

    Reviews

  • 23202530,27227299
  • Original publications

  • 17220230,9334321,20057119,22171814,25755103