RNase R, required for protection against paraquat stress
function
nonspecific degradation of rRNA
product
exoribonuclease RNase R (EC 3.1.-.-)
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.2|Biosynthesis/ acquisition of nucleotides] → [category|SW 2.5.2.5|Biosynthesis/ acquisition of nucleotides/ other][category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.4|RNases] → [category|SW 3.2.4.1|Exoribonucleases][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress][SW|Categories] containing this gene/protein
[SW|biosynthesis/ acquisition of nucleotides], [SW|RNAses], [SW|resistance against oxidative and electrophile stress]This gene is a member of the following [SW|regulons]
[SW|SigB regulon]Gene
Coordinates on the chromosome (coding sequence)
3,451,863 -> 3,454,202
The protein
Catalyzed reaction/ biological activity
3'-5'-exoribonucleaseProtein family
ribonuclease II (RNB) family (according to Swiss-Prot)Expression and Regulation
Operon
''[protein|search|secG]-[protein|search|yvaK]-[protein|search|rnr]-[protein|search|smpB]-[protein|search|ssrA]'' [Pubmed|17369301]''[protein|search|yvaK]-[protein|search|rnr]-[protein|search|smpB]-[protein|search|ssrA]'' [Pubmed|17369301][SW|Sigma factor]
''[protein|search|yvaK]'': [protein|search|SigB] [Pubmed|11544224]Regulation
''[protein|search|yvaK]'': induced by stress ([protein|search|SigB]) [Pubmed|11544224]Labs working on this gene/protein
[SW|David Bechhofer], Mount Sinai School, New York, USA [http://www.mountsinai.org/Research/Centers%20Laboratories%20and%20Programs/Bechhofer%20Laboratory?citype=Physician&ciid=Bechhofer%20David%20H%201255565 Homepage]References
Reviews
Original publications
15805528,15805522,20360175,17369301,23529473,22582280 
