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speA
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speA

arginine decarboxylase, required for biofilm formation
Locus
BSU_14630
Isoelectric point
5.08
Molecular weight
53.42 kDa
Protein length
490 aa Sequence Blast
Gene length
1470 bp Sequence Blast
Function
spermidine, polyamine biosynthesis
Product
arginine decarboxylase
Essential
no
E.C.
4.1.1.19
Synonyms
cad

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,534,279 → 1,535,751

Phenotypes of a mutant

The protein

Catalyzed reaction/ biological activity

  • H+ + L-arginine --> agmatine + CO2 (according to UniProt)
  • Protein family

  • Orn/Lys/Arg decarboxylase class-I family (together with YaaO) (according to UniProt)
  • Paralogous protein(s)

    Cofactors

  • PLP (according to UniProt)
  • Structure

  • 2X3L (from Staphylococcus aureus, 28% identity) PubMed
  • Localization

  • cytoplasm (according to Swiss-Prot)
  • Expression and Regulation

    Operons

    Biological materials

    Mutant

  • CS210 (speA::aphA3, available in Colin Harwood's and Jörg Stülke's labs) PubMed
  • BKE14630 (ΔspeA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAATTGTTTTCCCACCTTTG, downstream forward: _UP4_TAAAAAATAAAAAGCATGCG
  • BKK14630 (ΔspeA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAATTGTTTTCCCACCTTTG, downstream forward: _UP4_TAAAAAATAAAAAGCATGCG
  • References

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