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lnrJ [2020-04-14 18:47:29]
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lnrJ [2020-04-14 18:47:29]

two-component sensor kinase, involved in resistance to linearmycin
Locus
BSU_08290
Isoelectric point
6.39
Molecular weight
44.38 kDa
Protein length
400 aa Sequence Blast
Gene length
1203 bp Sequence Blast
Function
involved in resistance to linearmycin
Product
two-component sensor kinase
Essential
no
Synonyms
yfiJ
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Protein synthesis, modification and degradation → Protein modification → Protein kinases
  • Information processing → Regulation of gene expression → Transcription factors and their control → Control of two-component response regulators → Two-component sensor kinase
  • Groups of genes → Membrane proteins
  • Groups of genes → Phosphoproteins → Phosphorylation on a His residue

    • Gene

    Coordinates
    903,811 905,013

    The protein

    Catalyzed reaction/ biological activity

  • autophosphorylation, phosphorylation of LnrK
  • ATP + protein L-histidine --> ADP + protein N-phospho-L-histidine (according to UniProt)

    • Domains

  • 5 transmembrane segments
  • Histidine kinase domain (aa 190-385) (according to UniProt)

    • Modification

  • autophosphorylation on a His residue

    • Localization

  • cell membrane (according to UniProt)

    • Expression and Regulation

    Operons

    Genes
    lnrJ-lnrK
    Description
    PubMed
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    Biological materials

    Mutant

  • BKE08290 (lnrJ::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACGCTCATCACTCCCGATA, downstream forward: _UP4_GTGCAGCAAAAGGAGAGTTT
  • BKK08290 (lnrJ::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACGCTCATCACTCCCGATA, downstream forward: _UP4_GTGCAGCAAAAGGAGAGTTT

    • References

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