function
maturation of 23S rRNA
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.4|RNases] → [category|SW 3.2.4.2|Endoribonucleases][category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.2|rRNA modification and maturation][SW|Categories] containing this gene/protein
[SW|RNAses], [SW|translation]This gene is a member of the following [SW|regulons]
[SW|T-box]Gene
Coordinates on the chromosome (coding sequence)
114,854 -> 115,285
The protein
Protein family
[SW|RNase] III family (but lacks the dsRNA-binding domain)Effectors of protein activity
[protein|search|RplC] binding to the precursor 23S rRNA stimulates MrnC activity [Pubmed|19154332]Expression and Regulation
Operon
''[protein|search|gltX]-[protein|search|cysE]-[protein|search|cysS]-[protein|search|mrnC]-[protein|search|yacO]-[protein|search|yacP]'' [Pubmed|7510287][SW|Sigma factor]
[protein|search|SigA] [Pubmed|7510287]Regulation
repression by cysteine ([protein|search|T-box]) [Pubmed|7510287]Regulatory mechanism
[protein|search|T-box], overlaps a transcription terminator upstream of ''[protein|search|cysE]'': transcription antitermination [Pubmed|7510287]Labs working on this gene/protein
[SW|Ciaran Condon], IBPC, Paris, France [http://www.ibpc.fr/UPR9073/condon/index_en.html Homepage][SW|David Bechhofer], Mount Sinai School, New York, USA [http://www.mountsinai.org/Research/Centers Laboratories and Programs/Bechhofer Laboratory?citype=Physician&ciid=Bechhofer David H 1255565 Homepage]References
19258532,18430137,18363798,8396117,19154332,19880604,25634891,27924926 
