lytS [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

two-component sensor kinase, control of pyruvate utilization

locus: BSU28930

pI: 8.00

mw: 64.00 kDa

function: control of pyruvate utilization

product: two-component sensor kinase

essential: no

synonyms

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.3|Cell wall degradation/ turnover] → [category|SW 1.1.3.1|Autolysis]
• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.2|Protein kinases]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.1|Two-component sensor kinase]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.4|Phosphorylation on a His residue]

[SW|Categories] containing this gene/protein

• [SW|utilization of specific carbon sources], [SW|protein modification], [SW|transcription factors and their control], [SW|membrane proteins], [SW|phosphoproteins]

Gene

Coordinates on the chromosome (coding sequence): 2,956,486 -> 2,958,267

Phenotypes of a mutant

• no growth with pyruvate as the single carbon source [Pubmed|27422364]

The protein

Catalyzed reaction/ biological activity

• ATP [protein|search|LytT] = ADP [protein|search|LytT]-P

[SW|Domains]

• 5 transmembrane regions

Modification

• autophosphorylation on a His residue

[SW|Localization]

• membrane (putative, due to presence of 5 membrane-spanning domains)

[SW|Interactions]

• [protein|search|LytT]-[protein|search|LytS]

References

• 10094672,27422364