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pdeH [2017-8-11 16:0:3]
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pdeH [2017-8-11 16:0:3]

c-di-GMP degrading phosphodiesterase
Locus
BSU31740
Isoelectric point
5.36
Molecular weight
47.76 kDa
Protein length
409 aa Sequence Blast
Gene length
1227 bp Sequence Blast
Function
degradation of c-di-GMP
Product
c-di-GMP degrading phosphodiesterase
Essential
no
E.C.
3.1.3.71
Synonyms
yuxH, comB, yufA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Nucleotide metabolism → Metabolism of signalling nucleotides
  • Lifestyles → Exponential and early post-exponential lifestyles → Motility and chemotaxis → Signal transduction in motility and chemotaxis → Additional chemotaxis signal transduction and regulatory proteins

    • Gene

    Coordinates
    3,258,037 → 3,259,266

    The protein

    Catalyzed reaction/ biological activity

  • degradation of c-di-GMP PubMed

    • Protein family

  • comB family (according to Swiss-Prot)

    • Domains

  • contains an EAL domain PubMed

    • Expression and Regulation

    Operons

    Genes
    pdeH
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • Spo0A: repression, PubMed, in Spo0A regulon

    • Regulation

  • repressed under conditions that trigger sporulation (Spo0A) PubMed
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    Biological materials

    Mutant

  • MGNA-A606 (yufA/yuxH::erm), available at the NBRP B. subtilis, Japan
  • GP1590 (kan) available in Jörg Stülke's lab

    • References

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