SubtiBank SubtiBank
gmuB [2018-07-26 14:38:37]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

gmuB [2018-07-26 14:38:37]

glucomannan-specific phosphotransferase system, EIIB component of the PTS
Locus
BSU05810
Isoelectric point
4.72
Molecular weight
11.30 kDa
Protein length
103 aa Sequence Blast
Gene length
309 bp Sequence Blast
Function
glucomannan uptake and phosphorylation
Product
glucomannan-specific phosphotransferase system EIIB component
Essential
no
Synonyms
ydhM
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
Loading

Categories containing this gene/protein

  • Cellular processes → Transporters → Phosphotransferase system → Sugar specific PTS proteins
  • Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of glucomannan
  • Groups of genes → Phosphoproteins → Phosphorylation on a Cys residue

    • Gene

    Coordinates
    626,622 → 626,933

    The protein

    Protein family

  • lactose permease (Lac) EIIB family PubMed

    • Paralogous protein(s)

  • LicB

    • Structure

  • 4MGE (from B. anthracis, 46% identity)

    • Expression and Regulation

    Operons

    Genes
    gmuB-gmuA-gmuC-gmuD-gmuR-gmuE-gmuF-gmuG
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • GmuR: repression, PubMed, in GmuR regulon
  • CcpA: repression, PubMed, in CcpA regulon
  • AbrB: activation, PubMed, in AbrB regulon

    • Regulation

  • induced by cellobiose (GmuR) PubMed
    • view in new tab

    Biological materials

    Mutant

  • MGNA-C188 (ydhM::erm), available at the NBRP B. subtilis, Japan
  • BKE05810 (ΔgmuB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAACTGCTATCCCCCCTGTT, downstream forward: _UP4_TTGTCCTTAATGGTGAATCA
  • BKK05810 (ΔgmuB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAACTGCTATCCCCCCTGTT, downstream forward: _UP4_TTGTCCTTAATGGTGAATCA

    • References

    Loading