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roxS

small RNA, controls expression of ytdI, sucC-sucD, and yflS

Locus

BSU_misc_RNA_67

Function

control of ytdI, sucC-sucD, and yflS expression

Product

trans-acting regulatory RNA

Essential

Synonyms

rsaE

Genomic Context

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Categories containing this gene/protein

RNA

Catalyzed reaction/ biological activity

hybridizes to ytdI and sucD mRNAs to inhibit their translation and to destabilize them PubMed

binds the 5' end of the yflS mRNA to prevent its degradation by RNase J1 PubMed

Expression and Regulation

Operons

Genes

Description

Regulatory mechanism

ResD: transcriptional activation, PubMed, in ResD regulon

Regulation

induced by nitric oxide (NO) (ResD) PubMed

ResD: transcriptional activation PubMed

Rex: transcriptional repression PubMed

Additional information

the roxS RNA is degraded by the joined activities of RNase Y (initial endonucleolytic cleavage) and RNase J1 (processive degradation) PubMed

the roxS-ppnKB and roxS-sucC RNA duplexes form a cleavage site for RNase III PubMed

Biological materials

Mutant

available in Ciaran Condon's lab PubMed

References

Reviews

Research papers