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gerE
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gerE

transcriptional regulator (repressor or activator) of a subset of SigK-dependent late spore coat genes
Locus
BSU_28410
Isoelectric point
9.64
Molecular weight
8.43 kDa
Protein length
74 aa Sequence Blast
Gene length
225 bp Sequence Blast
Function
regulation of SigK-dependent gene expression
Product
transcriptional regulator (LuxR-FixJ family)
Essential
no
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Regulation of gene expression → Transcription factors and their control → Transcription factors/ other
  • Lifestyles → Sporulation → Germination → Additional germination proteins

    • Gene

    Coordinates
    2,904,727 2,904,951

    Phenotypes of a mutant

  • unable to germinate efficiently PubMed

    • The protein

    Protein family

  • LuxR-FixJ family of transcription regulators

    • Domains

  • HTH luxR-type domain (aa 5-70) (according to UniProt)

    • Structure

  • 1FSE

    • Additional information

  • information on binding sites can be found in the PRODORIC2 database

    • Expression and Regulation

    Operons

    Genes
    gerE
    Description
    PubMed

    Sigma factors

  • SigK: sigma factor, PubMed, in SigK regulon

    • Regulatory mechanism

  • SpoIIID: activation, PubMed, in SpoIIID regulon
  • CitB: mRNA binding, results in mRNA accumulation PubMed, in CitB regulon

    • Regulation

  • expressed late during sporulation in the mother cell (SigK, SpoIIID) PubMed
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    Biological materials

    Mutant

  • BKE28410 (gerE::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAGTATTGTAACCCTCCTT, downstream forward: _UP4_TAATCCTTGCCGGTATTCCT
  • BKK28410 (gerE::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAGTATTGTAACCCTCCTT, downstream forward: _UP4_TAATCCTTGCCGGTATTCCT

    • Labs working on this gene/protein

  • Arthur Aronson, Purdue University, West Lafayette, USA homepage
  • Charles Moran, Emory University, NC, USA homepage

    • References

    Reviews

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    Original Publications

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