SubtiBank SubtiBank
cotB
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

cotB

spore coat protein (outer)
Locus
BSU_36050
Isoelectric point
9.83
Molecular weight
42.81 kDa
Protein length
380 aa Sequence Blast
Gene length
1143 bp Sequence Blast
Function
resistance of the spore
Product
spore coat protein (outer)
Essential
no
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
Loading

Categories containing this gene/protein

  • Lifestyles → Sporulation → Sporulation proteins → Spore coat proteins → Class V
  • Groups of genes → Phosphoproteins → Phosphorylation on a Ser residue

    • Gene

    Coordinates
    3,714,739 3,715,881

    The protein

    Modification

  • phosphorylated on serine residues by CotH PubMed
  • maturation of CotB requires CotG PubMed

    • Localization

  • outer spore coat, at the middle of the spore as a ring- or spiral-like structure, localization depends on CotE PubMed

    • Expression and Regulation

    Operons

    Genes
    cotH-cotB-ywrJ
    Description
    PubMed

    Sigma factors

  • SigK: sigma factor, PubMed, in SigK regulon
  • SigE: sigma factor, PubMed, in SigE regulon

    • Regulatory mechanism

  • GerR: activation, PubMed, in GerR regulon
  • GerE: repression, PubMed, in GerE regulon
  • SpoIIID: activation, PubMed, in SpoIIID regulon

    • Regulation

  • expressed late during sporulation in the mother cell (SigE, SigK, GerE, SpoIIID) PubMed
    • view in new tab

    Genes
    cotB-ywrJ
    Description
    PubMed

    Regulation

  • expressed late during sporulation in the mother cell (SigE, SigK, GerE, GerR) PubMed
    • view in new tab

    Biological materials

    Mutant

  • 1S102 ( cotB::cat), PubMed, available at BGSC
  • BKE36050 (cotB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTCAAATTCCTCCTAGTC, downstream forward: _UP4_TAATAGATAATGGAGGAGCA
  • BKK36050 (cotB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTCAAATTCCTCCTAGTC, downstream forward: _UP4_TAATAGATAATGGAGGAGCA

    • References

    Loading