ykqA

168

putative gamma-glutamylcyclotransferase

locus: BSU_14500

Molecular weight: 31.51 kDa

pI: 6.22

Protein length: 277 aa

Gene length: 834 bp

function: unknown

product: unknown

essential: no

synonyms: ykqA, ylxU, yzaB

List of homologs in different organisms, belongs to COG3703 (Galperin et al., 2021)

Gene

Coordinates: 1,519,635  1,520,468

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The protein

Protein family

• gamma-glutamylcyclotransferase family (single member, according to UniProt)

Structure

• [PDB|2QIK]
• [AF|P39759]

Expression and Regulation

Operons

• genes: [gene|A656321846B2E0D1F39B528E2D8B8E620CCD1148|kinC]-[gene|22DBF4D1F93519A95E6BCC0FB1AC2387DF444E27|ykqA]-[gene|15F9BF08762D28CBCD3D9748EFBD29B0D6FD7623|ktrC]

  description: [Pubmed|22383849]

  regulation

  • constitutively expressed [Pubmed|12562800]

  regulatory mechanism

  • [protein|2C54FE2ADC82FF414D732018C90649D477A925AD|spo0A]: activation, [Pubmed|8002615], in [regulon|protein:2C54FE2ADC82FF414D732018C90649D477A925AD|spo0A regulon]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|8002614], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]

Biological materials

Mutant

• MGNA-A903 (ykqA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/903 NBRP B. subtilis, Japan]
• BKE14500 ([gene|22DBF4D1F93519A95E6BCC0FB1AC2387DF444E27|ykqA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE14500 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CGAGTTCACTTTATTTTTCT,  downstream forward: _UP4_TAACACTGTAACAAAAGAAT
• BKK14500 ([gene|22DBF4D1F93519A95E6BCC0FB1AC2387DF444E27|ykqA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK14500 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CGAGTTCACTTTATTTTTCT,  downstream forward: _UP4_TAACACTGTAACAAAAGAAT

References

• 22383849