YxbA

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  • Description: putative D-aspartate ligase

Gene name yxbA
Synonyms yxaO, aslA
Essential no
Product putative D-aspartate ligase
Function unknown
Gene expression levels in SubtiExpress: yxbA
Metabolic function and regulation of this protein in SubtiPathways:
Asp, Asn
MW, pI 10 kDa, 4.433
Gene length, protein length 267 bp, 89 aa
Immediate neighbours yxbB, yxnB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YxbA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YxbA expression.png




























Categories containing this gene/protein

poorly characterized/ putative enzymes, sporulation proteins

This gene is a member of the following regulons

AbrB regulon, CodY regulon

The gene

Basic information

  • Locus tag: BSU39900

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by glucose (8-fold) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • repressed during logrithmic growth (AbrB) PubMed
  • Additional information:
    • the tricistronic yxbB-yxbA-yxnB transcript is extremely stable, and stability is mediated by a 5'-proximal long sequence triplication preceding the yxbB open reading frame PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References