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Gene name yvrHa
Synonyms rsoA
Essential write here
Product co-sigma factor (with YvrI)
Function RNA polymerase sigma factor
MW, pI 9.5 kDa, 4.69
Gene length, protein length 240 bp, 79 amino acids
Immediate neighbours yvrHb, yvrI
Gene sequence (+200bp) Protein sequence
Genetic context
YvrHa yvrHb context.GIF

The gene

Basic information

  • Locus tag:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: does not exist

Additional information

The sequence of the former yvrH gene was corrected, and does now contain two genes, yvrHa and yvrHb.

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: no entry
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: induced by acidic growth conditions PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage

Your additional remarks


Shawn R MacLellan, Veronica Guariglia-Oropeza, Ahmed Gaballa, John D Helmann
A two-subunit bacterial sigma-factor activates transcription in Bacillus subtilis.
Proc. Natl. Acad. Sci. U.S.A.: 2009, 106(50);21323-8
[PubMed:19940246] [WorldCat.org] [DOI] (I p)

Shawn R MacLellan, John D Helmann, Haike Antelmann
The YvrI alternative sigma factor is essential for acid stress induction of oxalate decarboxylase in Bacillus subtilis.
J. Bacteriol.: 2009, 191(3);931-9
[PubMed:19047353] [WorldCat.org] [DOI] (I p)

Shawn R MacLellan, Tina Wecke, John D Helmann
A previously unidentified sigma factor and two accessory proteins regulate oxalate decarboxylase expression in Bacillus subtilis.
Mol. Microbiol.: 2008, 69(4);954-67
[PubMed:18573182] [WorldCat.org] [DOI] (I p)