Difference between revisions of "YvaK"

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* '''Operon:'''  
* '''Operon:'''  
** ''[[secG]]-[[yvaK]]-[[rnr]]-[[smpB]]-[[ssrA]]'' {{PubMed|17369301}}
** ''[[yvaK]]-[[rnr]]-[[smpB]]-[[ssrA]]'' {{PubMed|17369301}}
* '''[[Sigma factor]]:''' [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed]  
* '''[[Sigma factor]]:'''  
** ''[[yvaK]]'': [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed]  
* '''Regulation:'''  induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed]
* '''Regulation:'''   
** ''[[yvaK]]'': induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed]
* '''Regulatory mechanism:'''  
* '''Regulatory mechanism:'''  
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<pubmed>11544224, </pubmed>
<pubmed>11544224, 17369301</pubmed>
[[Category:Protein-coding genes]]
[[Category:Protein-coding genes]]

Revision as of 08:33, 3 February 2011

  • Description: general stress protein, similar to carboxylesterase

Gene name yvaK
Essential no
Product unknown
Function unknown
MW, pI 28 kDa, 4.992
Gene length, protein length 744 bp, 248 aa
Immediate neighbours rnr, secG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YvaK context.gif
This image was kindly provided by SubtiList

Categories containing this gene/protein

general stress proteins (controlled by SigB), poorly characterized/ putative enzymes

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

  • Locus tag: BSU33620

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: A carboxylic ester + H2O = an alcohol + a carboxylate (according to Swiss-Prot)
  • Protein family: lipase/esterase LIP3/bchO family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 1TQH (Geobacillus stearothermophilus)
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


Ji-Hyun Shin, Chester W Price
The SsrA-SmpB ribosome rescue system is important for growth of Bacillus subtilis at low and high temperatures.
J. Bacteriol.: 2007, 189(10);3729-37
[PubMed:17369301] [WorldCat.org] [DOI] (P p)

A Petersohn, M Brigulla, S Haas, J D Hoheisel, U Völker, M Hecker
Global analysis of the general stress response of Bacillus subtilis.
J. Bacteriol.: 2001, 183(19);5617-31
[PubMed:11544224] [WorldCat.org] [DOI] (P p)