Difference between revisions of "YpmP"

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=The gene=
 
=The gene=

Revision as of 17:02, 22 June 2009

  • Description: unknown

Gene name ypmP
Synonyms
Essential no
Product unknown
Function unknown
Metabolic function and regulation of this protein in SubtiPathways:
Ile, Leu, Val
MW, pI 10 kDa, 9.945
Gene length, protein length 249 bp, 83 aa
Immediate neighbours ypmQ, ilvA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YpmP context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU21760

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: repressed by casamino acids PubMed, repressed by CodY PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Regulatory mechanism: CodY: transcription repression PubMed
  • Additional information:

Biological materials

  • Mutant: GP564, aphA3, available in the Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Ulrike Mäder, Susanne Hennig, Michael Hecker, Georg Homuth
Transcriptional organization and posttranscriptional regulation of the Bacillus subtilis branched-chain amino acid biosynthesis genes.
J. Bacteriol.: 2004, 186(8);2240-52
[PubMed:15060025] [WorldCat.org] [DOI] (P p)

Virginie Molle, Yoshiko Nakaura, Robert P Shivers, Hirotake Yamaguchi, Richard Losick, Yasutaro Fujita, Abraham L Sonenshein
Additional targets of the Bacillus subtilis global regulator CodY identified by chromatin immunoprecipitation and genome-wide transcript analysis.
J. Bacteriol.: 2003, 185(6);1911-22
[PubMed:12618455] [WorldCat.org] [DOI] (P p)