Difference between revisions of "YisP"

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'''Additional publications:''' {{PubMed|23295493}}
<pubmed> 20713508 19935659</pubmed>
<pubmed> 20713508 19935659 23651456 23295493</pubmed>
[[Category:Protein-coding genes]]
[[Category:Protein-coding genes]]

Revision as of 11:48, 10 May 2013

  • Description: production of squalene-derived polyisoprenoids

Gene name yisP
Synonyms yucD
Essential no
Product squalene synthase
Function control of KinC activity
Gene expression levels in SubtiExpress: yisP
MW, pI 31 kDa, 7.258
Gene length, protein length 822 bp, 274 aa
Immediate neighbours yizA, yisQ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YisP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YisP expression.png

Categories containing this gene/protein

biosynthesis of lipids, phosphorelay, biofilm formation

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU10810

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

The gene is annotated in KEGG as an ortholog of phytoene synthase EC No EC annotation is available in Swiss-Prot/MetaCSwiss-Prot/MetaCyc.literature/experimental evidence supporting the annotation is available. PubMed

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


Juri Niño Bach, Marc Bramkamp
Flotillins functionally organize the bacterial membrane.
Mol Microbiol: 2013, 88(6);1205-17
[PubMed:23651456] [WorldCat.org] [DOI] (I p)

Yumei Hu, Shiru Jia, Feifei Ren, Chun Hsiang Huang, Tzu Ping Ko, Douglas A Mitchell, Rey Ting Guo, Yingying Zheng
Crystallization and preliminary X-ray diffraction analysis of YisP protein from Bacillus subtilis subsp. subtilis strain 168.
Acta Crystallogr Sect F Struct Biol Cryst Commun: 2013, 69(Pt 1);77-9
[PubMed:23295493] [WorldCat.org] [DOI] (I p)

Daniel López, Roberto Kolter
Functional microdomains in bacterial membranes.
Genes Dev: 2010, 24(17);1893-902
[PubMed:20713508] [WorldCat.org] [DOI] (I p)

Tzu-Lin Hsiao, Olga Revelles, Lifeng Chen, Uwe Sauer, Dennis Vitkup
Automatic policing of biochemical annotations using genomic correlations.
Nat Chem Biol: 2010, 6(1);34-40
[PubMed:19935659] [WorldCat.org] [DOI] (I p)