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  • Description: uracil phosphoribosyltransferase

Gene name upp
Synonyms ipc-35d
Essential no
Product uracil phosphoribosyltransferase
Function UMP synthesis
Metabolic function and regulation of this protein in SubtiPathways:
Pyrimidines, Nucleotides (regulation)
MW, pI 22 kDa, 5.863
Gene length, protein length 627 bp, 209 aa
Immediate neighbours frr, cdsA
Gene sequence (+200bp) Protein sequence
Genetic context
Upp context.gif
This image was kindly provided by SubtiList

The gene

Basic information

  • Locus tag: BSU36890

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate (according to Swiss-Prot)
  • Protein family: UPRTase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


J Martinussen, P Glaser, P S Andersen, H H Saxild
Two genes encoding uracil phosphoribosyltransferase are present in Bacillus subtilis.
J. Bacteriol.: 1995, 177(1);271-4
[PubMed:7798145] [WorldCat.org] [DOI] (P p)