ThyB

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  • Description: thymidylate synthase B

Gene name thyB
Synonyms
Essential no
Product thymidylate synthase B
Function biosynthesis of thymidine nucleotides
Metabolic function and regulation of this protein in SubtiPathways:
Nucleotides (regulation)
MW, pI 30 kDa, 6.272
Gene length, protein length 792 bp, 264 aa
Immediate neighbours dfrA, ypjQ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ThyB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU21820

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References