Difference between revisions of "ThyA"

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* '''Locus tag:''' BSU17680
* '''Locus tag:''' BSU17680
[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=thyA_1902219_1903058_1 Expression]
===Phenotypes of a mutant ===
===Phenotypes of a mutant ===

Revision as of 09:43, 28 January 2012

  • Description: thymidylate synthase A

Gene name thyA
Essential no
Product thymidylate synthase A
Function biosynthesis of thymidine nucleotides
MW, pI 32 kDa, 5.502
Gene length, protein length 837 bp, 279 aa
Immediate neighbours cotU, yncM
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ThyA context.gif
This image was kindly provided by SubtiList

Categories containing this gene/protein

biosynthesis/ acquisition of nucleotides

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU17680

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP (according to Swiss-Prot)
  • Protein family: Bacterial-type thyA subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


A Yazgan, G Ozcengiz, M A Marahiel
Tn10 insertional mutations of Bacillus subtilis that block the biosynthesis of bacilysin.
Biochim Biophys Acta: 2001, 1518(1-2);87-94
[PubMed:11267663] [WorldCat.org] [DOI] (P p)