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  • Description: ABC transporter for teichoic acid translocation (ATP-binding protein)

Gene name tagH
Essential yes PubMed
Product ABC transporter for teichoic acid translocation (ATP-binding protein)
Function biosynthesis of teichoic acid
Gene expression levels in SubtiExpress: tagH
Interactions involving this protein in SubtInteract: TagH
MW, pI 59 kDa, 9.447
Gene length, protein length 1581 bp, 527 aa
Immediate neighbours yvzE, tagG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
TagH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TagH expression.png

Categories containing this gene/protein

cell wall synthesis, ABC transporters, biosynthesis of cell wall components, essential genes, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU35700

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + H2O + teichoic acid(In) = ADP + phosphate + teichoic acid(Out) (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


Kathrin Schirner, Laura K Stone, Suzanne Walker
ABC transporters required for export of wall teichoic acids do not discriminate between different main chain polymers.
ACS Chem Biol: 2011, 6(5);407-12
[PubMed:21280653] [WorldCat.org] [DOI] (I p)

Alex Formstone, Rut Carballido-López, Philippe Noirot, Jeffery Errington, Dirk-Jan Scheffers
Localization and interactions of teichoic acid synthetic enzymes in Bacillus subtilis.
J Bacteriol: 2008, 190(5);1812-21
[PubMed:18156271] [WorldCat.org] [DOI] (I p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)

V Lazarevic, D Karamata
The tagGH operon of Bacillus subtilis 168 encodes a two-component ABC transporter involved in the metabolism of two wall teichoic acids.
Mol Microbiol: 1995, 16(2);345-55
[PubMed:7565096] [WorldCat.org] [DOI] (P p)