Difference between revisions of "SpoIVB"

From SubtiWiki
Jump to: navigation, search
(Extended information on the protein)
Line 1: Line 1:
* '''Description:''' transmembrane serine peptidase<br/><br/>
+
* '''Description:''' serine protease, cleaves SpoIVFA, this results in pro-sigma-K processing/activation in the mother-cell, does also cleave CtpB <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
Line 10: Line 10:
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || serine peptidase of the SA clan
+
|style="background:#ABCDEF;" align="center"| '''Product''' || serine protease
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || intercompartmental signalling of pro-sigma-K processing in the mother-cell
+
|style="background:#ABCDEF;" align="center"|'''Function''' || control of SigK activation
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 45 kDa, 8.842   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 45 kDa, 8.842   

Revision as of 10:29, 15 April 2009

  • Description: serine protease, cleaves SpoIVFA, this results in pro-sigma-K processing/activation in the mother-cell, does also cleave CtpB

Gene name spoIVB
Synonyms
Essential no
Product serine protease
Function control of SigK activation
MW, pI 45 kDa, 8.842
Gene length, protein length 1275 bp, 425 aa
Immediate neighbours spo0A, recN
Gene sequence (+200bp) Protein sequence
Caution: The sequence for this gene in SubtiList contains errors
Genetic context
SpoIVB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Simon Cutting, London, UK homepage

Your additional remarks

References

  1. Dong & Cutting (2004) The PDZ domain of the SpoIVB transmembrane signaling protein enables cis-trans interactions involving multiple partners leading to the activation of the pro-sigmaK processing complex in Bacillus subtilis.J. Biol. Chem. 279: 43468-43478. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed