From SubtiWiki
Revision as of 04:42, 25 June 2009 by Sroppel (talk | contribs)
Jump to: navigation, search
  • Description: required for SigG activation

Gene name spoIIIAH
Essential no
Product unknown
Function activation of SigG
MW, pI 23 kDa, 4.627
Gene length, protein length 654 bp, 218 aa
Immediate neighbours accB, spoIIIAG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SpoIIIAH context.gif
This image was kindly provided by SubtiList

The gene

Basic information

  • Locus tag: BSU24360

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: membrane protein PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Additional information: the internal promoter is essential for sporulation, it is twice as active as the promoter in front of spoIIIAA, suggesting that SpoIIIAG and SpoIIIAH are required in larger amounts as compared to the other products of the operon PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


Jeffrey Meisner, Xin Wang, Monica Serrano, Adriano O Henriques, Charles P Moran
A channel connecting the mother cell and forespore during bacterial endospore formation.
Proc. Natl. Acad. Sci. U.S.A.: 2008, 105(39);15100-5
[PubMed:18812514] [WorldCat.org] [DOI] (I p)

Amy H Camp, Richard Losick
A novel pathway of intercellular signalling in Bacillus subtilis involves a protein with similarity to a component of type III secretion channels.
Mol. Microbiol.: 2008, 69(2);402-17
[PubMed:18485064] [WorldCat.org] [DOI] (I p)

Chris Guillot, Charles P Moran
Essential internal promoter in the spoIIIA locus of Bacillus subtilis.
J. Bacteriol.: 2007, 189(20);7181-9
[PubMed:17693505] [WorldCat.org] [DOI] (P p)

Thierry Doan, Kathleen A Marquis, David Z Rudner
Subcellular localization of a sporulation membrane protein is achieved through a network of interactions along and across the septum.
Mol. Microbiol.: 2005, 55(6);1767-81
[PubMed:15752199] [WorldCat.org] [DOI] (P p)

Bill Blaylock, Xin Jiang, Aileen Rubio, Charles P Moran, Kit Pogliano
Zipper-like interaction between proteins in adjacent daughter cells mediates protein localization.
Genes Dev.: 2004, 18(23);2916-28
[PubMed:15574594] [WorldCat.org] [DOI] (P p)

N Illing, J Errington
The spoIIIA operon of Bacillus subtilis defines a new temporal class of mother-cell-specific sporulation genes under the control of the sigma E form of RNA polymerase.
Mol. Microbiol.: 1991, 5(8);1927-40
[PubMed:1766372] [WorldCat.org] [DOI] (P p)