SbcD

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  • Description: exonuclease SbcD homolog

Gene name sbcD
Synonyms yixA
Essential no
Product exonuclease SbcD homolog
Function unknown
MW, pI 43 kDa, 5.003
Gene length, protein length 1173 bp, 391 aa
Immediate neighbours addA, sbcC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SbcD context.gif
This image was kindly provided by SubtiList





Categories containing this gene/protein

DNA repair/ recombination, genetic competence

This gene is a member of the following regulons

ComK regulon

The gene

Basic information

  • Locus tag: BSU10640

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: sbcD family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: Cytoplasm (Homogeneous) PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
    • GP894 (sbcCD::kan), available in Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)

Mitsuo Ogura, Hirotake Yamaguchi, Kazuo Kobayashi, Naotake Ogasawara, Yasutaro Fujita, Teruo Tanaka
Whole-genome analysis of genes regulated by the Bacillus subtilis competence transcription factor ComK.
J. Bacteriol.: 2002, 184(9);2344-51
[PubMed:11948146] [WorldCat.org] [DOI] (P p)

G J Sharples, R G Lloyd
Location of the Bacillus subtilis sbcD gene downstream of addAB, the analogues of E. coli recBC.
Nucleic Acids Res.: 1993, 21(8);2010
[PubMed:8493111] [WorldCat.org] [DOI] (P p)