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  • Description: deoxyadenosin/deoxycytidine kinase

Gene name dck
Synonyms yaaF
Essential no
Product deoxyadenosin/deoxycytidine kinase
Function purine salvage and interconversion
Gene expression levels in SubtiExpress: dck
Metabolic function and regulation of this protein in SubtiPathways:
Purine salvage, Nucleotides (regulation)
MW, pI 25 kDa, 5.536
Gene length, protein length 651 bp, 217 aa
Immediate neighbours trnSL-Ser1, dgk
Sequences Protein DNA DNA_with_flanks
Genetic context
Dck context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Dck expression.png

Categories containing this gene/protein

biosynthesis/ acquisition of nucleotides

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU00140

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


R B Andersen, J Neuhard
Deoxynucleoside kinases encoded by the yaaG and yaaF genes of Bacillus subtilis. Substrate specificity and kinetic analysis of deoxyguanosine kinase with UTP as the preferred phosphate donor.
J Biol Chem: 2001, 276(8);5518-24
[PubMed:11078735] [] [DOI] (P p)

H Møllgaard
Deoxyadenosine/deoxycytidine kinase from Bacillus subtilis. Purification, characterization, and physiological function.
J Biol Chem: 1980, 255(17);8216-20
[PubMed:6251049] [] (P p)