Difference between revisions of "RelA"

From SubtiWiki
Jump to: navigation, search
Line 33: Line 33:
=The gene=
=The gene=

Revision as of 08:58, 23 June 2009

  • Description: GTP pyrophosphokinase (stringent response)

Gene name relA
Essential no
Product GTP pyrophosphokinase
Function synthesis and degradation of (p)ppGpp,
triggering the stringent response
Metabolic function and regulation of this protein in SubtiPathways:
Purine salvage, Nucleotides (regulation)
MW, pI 84 kDa, 6.964
Gene length, protein length 2202 bp, 734 aa
Immediate neighbours yrvI, apt
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RelA context.gif
This image was kindly provided by SubtiList

The gene

Basic information

  • Locus tag: BSU27600

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate (according to Swiss-Prot)
  • Protein family: relA/spoT family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Mohamed Marahiel, Marburg University, Germany homepage

Your additional remarks