Difference between revisions of "PurA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || purine biosynthesis | |style="background:#ABCDEF;" align="center"|'''Function''' || purine biosynthesis | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU40420 purA] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/purines_salvage_pathways.html Purine salvage], [http://subtiwiki.uni-goettingen.de/pathways/purine_biosynthesis.html Purine synthesis], [http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/purines_salvage_pathways.html Purine salvage], [http://subtiwiki.uni-goettingen.de/pathways/purine_biosynthesis.html Purine synthesis], [http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[trnY-Lys]]'', ''[[yycE]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[trnY-Lys]]'', ''[[yycE]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU40420 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU40420 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU40420 Advanced_DNA] |
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|colspan="2" | '''Genetic context''' <br/> [[Image:purA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:purA_context.gif]] | ||
Revision as of 14:19, 13 May 2013
- Description: adenylosuccinate synthetase
| Gene name | purA |
| Synonyms | |
| Essential | no |
| Product | adenylosuccinate synthetase |
| Function | purine biosynthesis |
| Gene expression levels in SubtiExpress: purA | |
| Metabolic function and regulation of this protein in SubtiPathways: Purine salvage, Purine synthesis, Nucleotides (regulation) | |
| MW, pI | 47 kDa, 5.459 |
| Gene length, protein length | 1290 bp, 430 aa |
| Immediate neighbours | trnY-Lys, yycE |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU40420
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: GTP + IMP + L-aspartate = GDP + phosphate + N(6)-(1,2-dicarboxyethyl)-AMP (according to Swiss-Prot)
- Protein family: adenylosuccinate synthetase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- phosphorylated on Arg-97 PubMed
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: P29726
- KEGG entry: [3]
- E.C. number: 6.3.4.4
Additional information
Expression and regulation
- Operon: purA PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
