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  • Description: similar to A/G-specific adenine glycosylase

Gene name yfhQ
Essential no
Product error prevention oxidized guanine system
Function DNA repair
Metabolic function and regulation of this protein in SubtiPathways:
Lipid synthesis
MW, pI 41 kDa, 6.044
Gene length, protein length 1107 bp, 369 aa
Immediate neighbours yfhP, yfhS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YfhQ context.gif
This image was kindly provided by SubtiList

The gene

Basic information

  • Locus tag: BSU08630

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 1RRS (complex with DNA, Geobacillus stearothermophilus)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • YfhP may act as a negative transcription regulator of the yfhQ-fabL-sspE operon during exponential growth PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


Luz E Vidales, Lluvia C Cárdenas, Eduardo Robleto, Ronald E Yasbin, Mario Pedraza-Reyes
Defects in the error prevention oxidized guanine system potentiate stationary-phase mutagenesis in Bacillus subtilis.
J Bacteriol: 2009, 191(2);506-13
[PubMed:19011023] [] [DOI] (I p)

Hiroki Yamamoto, Masao Mori, Junichi Sekiguchi
Transcription of genes near the sspE locus of the Bacillus subtilis genome.
Microbiology (Reading): 1999, 145 ( Pt 8);2171-2180
[PubMed:10463184] [] [DOI] (P p)