MenA

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  • Description: probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Gene name menA
Synonyms ywaB, ipa-6d
Essential yes PubMed
Product probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase
Function biosynthesis of menaquinone
Gene expression levels in SubtiExpress: menA
Metabolic function and regulation of this protein in SubtiPathways:
Menaquinone
MW, pI 33 kDa, 9.32
Gene length, protein length 933 bp, 311 aa
Immediate neighbours ywaC, ywzH
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MenA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MenA expression.png




























Categories containing this gene/protein

biosynthesis of cofactors, essential genes, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU38490

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: menA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

E Presecan, I Moszer, L Boursier, H C Cruz Ramos, V de la Fuente, M F Hullo, C Lelong, S Schleich, A Sekowska, B H Song, G Villani, F Kunst, A Danchin, P Glaser
The Bacillus subtilis genome from gerBC (311 degrees) to licR (334 degrees).
Microbiology (Reading): 1997, 143 ( Pt 10);3313-28
[PubMed:9353933] [WorldCat.org] [DOI] (P p)