From SubtiWiki
Revision as of 08:46, 23 June 2009 by CLammers (talk | contribs)
Jump to: navigation, search
  • Description: methionine aminopeptidase

Gene name map
Essential yes PubMed
Product methionine aminopeptidase
Function removal of N-terminal methionine from nascent proteins
Metabolic function and regulation of this protein in SubtiPathways:
Nucleotides (regulation)
MW, pI 27 kDa, 6.393
Gene length, protein length 744 bp, 248 aa
Immediate neighbours adk, infA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Map context.gif
This image was kindly provided by SubtiList

The gene

Basic information

  • Locus tag: BSU01380

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides (according to Swiss-Prot)
  • Protein family: peptidase M24A family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: strongly expressed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


CongHui You, HongYan Lu, Agnieszka Sekowska, Gang Fang, YiPing Wang, Anne-Marie Gilles, Antoine Danchin
The two authentic methionine aminopeptidase genes are differentially expressed in Bacillus subtilis.
BMC Microbiol.: 2005, 5;57
[PubMed:16207374] [] [DOI] (I e)

J W Suh, S A Boylan, S H Oh, C W Price
Genetic and transcriptional organization of the Bacillus subtilis spc-alpha region.
Gene: 1996, 169(1);17-23
[PubMed:8635744] [] [DOI] (P p)