Difference between revisions of "KtrB"

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= [[Categories]] containing this gene/protein =
= [[Categories]] containing this gene/protein =
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* '''Regulation:'''  
* '''Regulation:'''  
** induced if the energy charge is low ([[ydaO riboswitch]])  {{PubMed|23086297}}
* '''Regulatory mechanism:'''  
* '''Regulatory mechanism:'''  
** expression is controlled via termination antitermination by the [[ydaO riboswitch]] {{PubMed|20511502}}  
** expression is controlled via termination antitermination by the [[ydaO riboswitch]] {{PubMed|23086297,20511502}}  
* '''Additional information:'''
* '''Additional information:'''
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<pubmed>12562800,20511502, 17932047 </pubmed>
<pubmed>12562800,20511502, 17932047 23086297</pubmed>
[[Category:Protein-coding genes]]
[[Category:Protein-coding genes]]

Revision as of 16:08, 23 October 2012

  • Description: high affinity potassium transporter KtrA-KtrB, integral membrane subunit

Gene name ktrB
Synonyms yubG
Essential no
Product high affinity potassium transporter KtrA-KtrB,
integral membrane subunit (proton symport)
Function potassium uptake
Gene expression levels in SubtiExpress: ktrB
Interactions involving this protein in SubtInteract: KtrB
Metabolic function and regulation of this protein in SubtiPathways:
Metal ion homeostasis, Stress
MW, pI 48 kDa, 10.116
Gene length, protein length 1335 bp, 445 aa
Immediate neighbours ktrA, yubF
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YubG context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
KtrB expression.png

Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), coping with hyper-osmotic stress, membrane proteins

This gene is a member of the following regulons

YdaO riboswitch

The gene

Basic information

  • Locus tag: BSU31100

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): KtrD

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Erhard Bremer, University of Marburg, Germany homepage

Your additional remarks


Peter Y Watson, Martha J Fedor
The ydaO motif is an ATP-sensing riboswitch in Bacillus subtilis.
Nat Chem Biol: 2012, 8(12);963-5
[PubMed:23086297] [WorldCat.org] [DOI] (I p)

Kirsten F Block, Ming C Hammond, Ronald R Breaker
Evidence for widespread gene control function by the ydaO riboswitch candidate.
J Bacteriol: 2010, 192(15);3983-9
[PubMed:20511502] [WorldCat.org] [DOI] (I p)

Ronald A Albright, Kyu Joh, João H Morais-Cabral
Probing the structure of the dimeric KtrB membrane protein.
J Biol Chem: 2007, 282(48);35046-55
[PubMed:17932047] [WorldCat.org] [DOI] (P p)

Gudrun Holtmann, Evert P Bakker, Nobuyuki Uozumi, Erhard Bremer
KtrAB and KtrCD: two K+ uptake systems in Bacillus subtilis and their role in adaptation to hypertonicity.
J Bacteriol: 2003, 185(4);1289-98
[PubMed:12562800] [WorldCat.org] [DOI] (P p)