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  • Description: similar to serine protease HtrA

Gene name yyxA
Synonyms yycK
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: yyxA
MW, pI 42 kDa, 5.315
Gene length, protein length 1200 bp, 400 aa
Immediate neighbours yyzO, walJ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YyxA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YyxA expression.png

Categories containing this gene/protein

proteolysis, sporulation proteins, membrane proteins

This gene is a member of the following regulons

SigG regulon

The gene

Basic information

  • Locus tag: BSU40360

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase S1B family (according to Swiss-Prot)
  • Paralogous protein(s): HtrA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

yyxA PubMed

  • Regulation: expressed during vegetative growth, repressed during stationary phase PubMed

yyxA transcript expressed during sporulation PubMed

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


Elodie Marchadier, Rut Carballido-López, Sophie Brinster, Céline Fabret, Peggy Mervelet, Philippe Bessières, Marie-Françoise Noirot-Gros, Vincent Fromion, Philippe Noirot
An expanded protein-protein interaction network in Bacillus subtilis reveals a group of hubs: Exploration by an integrative approach.
Proteomics: 2011, 11(15);2981-91
[PubMed:21630458] [] [DOI] (I p)

C Fabret, J A Hoch
A two-component signal transduction system essential for growth of Bacillus subtilis: implications for anti-infective therapy.
J. Bacteriol.: 1998, 180(23);6375-83
[PubMed:9829949] [] (P p)