Difference between revisions of "GlpX"

From SubtiWiki
Jump to: navigation, search
(Database entries)
Line 84: Line 84:
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU37090]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU37090]
* '''E.C. number:'''
* '''E.C. number:'''
=== Additional information===
=== Additional information===

Revision as of 15:18, 18 June 2009

  • Description: class II fructose-1,6-bisphosphatase, gluconeogenesis

Gene name glpX
Synonyms ywjI
Essential no
Product class II fructose-1,6-bisphosphatase
Function gluconeogenesis
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism, Sugar catabolism
MW, pI 33 kDa, 5.067
Gene length, protein length 963 bp, 321 aa
Immediate neighbours rho, murAB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YwjI context.gif
This image was kindly provided by SubtiList

The gene

Basic information

  • Locus tag: BSU37090

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: D-fructose 1,6-bisphosphate ==> D-fructose 6-phosphate + Pi
  • Protein family: FBPase class 2 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information: K(M) for FBP: 20 µM PubMed
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: constitutive PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


Matthieu Jules, Ludovic Le Chat, Stéphane Aymerich, Dominique Le Coq
The Bacillus subtilis ywjI (glpX) gene encodes a class II fructose-1,6-bisphosphatase, functionally equivalent to the class III Fbp enzyme.
J. Bacteriol.: 2009, 191(9);3168-71
[PubMed:19270101] [WorldCat.org] [DOI] (I p)