Difference between revisions of "GamA"

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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 747 bp, 249 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 747 bp, 249 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[gamP]]'', ''[[ybgA]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[gamP]]'', ''[[gamR]]''
 
|-
 
|-
 
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02360 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02360 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02360 DNA_with_flanks]
 
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02360 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02360 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02360 DNA_with_flanks]
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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[YbgA regulon]]}}
+
{{SubtiWiki regulon|[[GamR regulon]]}}
  
 
=The gene=
 
=The gene=
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* '''Regulation:'''  
 
* '''Regulation:'''  
 
** induced by N-acetylglucosamine {{PubMed|14343123}}  
 
** induced by N-acetylglucosamine {{PubMed|14343123}}  
** induced by glucosamine ([[YbgA]]) {{PubMed|23667565}}  
+
** induced by glucosamine ([[GamR]]) {{PubMed|23667565}}  
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
** [[YbgA]]: transcription repression {{PubMed|23667565}}  
+
** [[GamR]]: transcription repression {{PubMed|23667565}}  
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 07:41, 31 March 2014

  • Description: glucosamine-6-phosphate deaminase

Gene name gamA
Synonyms ybfT
Essential no
Product glucosamine-6-phosphate deaminase
Function glucosamine utilization
Gene expression levels in SubtiExpress: gamA
Metabolic function and regulation of this protein in SubtiPathways:
gamA
MW, pI 27 kDa, 5.793
Gene length, protein length 747 bp, 249 aa
Immediate neighbours gamP, gamR
Sequences Protein DNA DNA_with_flanks
Genetic context
GamA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
GamA expression.png















Categories containing this gene/protein

cell wall degradation/ turnover, utilization of specific carbon sources

This gene is a member of the following regulons

GamR regulon

The gene

Basic information

  • Locus tag: BSU02360

Phenotypes of a mutant

  • no growth on glucosamine PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: d-glucosamine 6-phosphate + H2O = D-fructose 6-phosphate + NH3 (according to Swiss-Prot)
  • Protein family: NagB subfamily (according to Swiss-Prot)
  • Paralogous protein(s): NagB

Extended information on the protein

  • Kinetic information: K(M): 3.0 mM PubMed
  • Modification:
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References