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  • Description: fatty acid degradation, similar to proline dehydrogenase

Gene name fadM
Synonyms yusM
Essential no
Product unknown
Function fatty acid degradation
Gene expression levels in SubtiExpress: fadM
Metabolic function and regulation of this protein in SubtiPathways:
Fatty acid degradation
MW, pI 34 kDa, 9.377
Gene length, protein length 906 bp, 302 aa
Immediate neighbours yuzL, yusN
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YusM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FadM expression.png

Categories containing this gene/protein

utilization of lipids

This gene is a member of the following regulons

FadR regulon, SdpR regulon

The gene

Basic information

  • Locus tag: BSU32850

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor (according to Swiss-Prot)
  • Protein family: proline dehydrogenase family (according to Swiss-Prot)
  • Paralogous protein(s): PutB

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


Hiroshi Matsuoka, Kazutake Hirooka, Yasutaro Fujita
Organization and function of the YsiA regulon of Bacillus subtilis involved in fatty acid degradation.
J Biol Chem: 2007, 282(8);5180-94
[PubMed:17189250] [WorldCat.org] [DOI] (P p)

José E González-Pastor, Errett C Hobbs, Richard Losick
Cannibalism by sporulating bacteria.
Science: 2003, 301(5632);510-3
[PubMed:12817086] [WorldCat.org] [DOI] (I p)