Dps

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  • Description: iron storage protein, general stress protein, resistance against ethanol stress and survival at low temperatures

Gene name dps
Synonyms ytkB
Essential no
Product mini-ferritin
Function iron storage
Gene expression levels in SubtiExpress: dps
MW, pI 16 kDa, 4.444
Gene length, protein length 435 bp, 145 aa
Immediate neighbours ytkC, ytzI
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Dps context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Dps expression.png
























Categories containing this gene/protein

acquisition of iron, iron metabolism, general stress proteins (controlled by SigB)

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

  • Locus tag: BSU30650

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: dps family (according to Swiss-Prot)
  • Paralogous protein(s): MrgA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Emilia Chiancone, Pierpaolo Ceci, Andrea Ilari, Frederica Ribacchi, Simonetta Stefanini
Iron and proteins for iron storage and detoxification.
Biometals: 2004, 17(3);197-202
[PubMed:15222465] [WorldCat.org] [DOI] (P p)

Original publications

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J. Bacteriol.: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

H Antelmann, S Engelmann, R Schmid, A Sorokin, A Lapidus, M Hecker
Expression of a stress- and starvation-induced dps/pexB-homologous gene is controlled by the alternative sigma factor sigmaB in Bacillus subtilis.
J. Bacteriol.: 1997, 179(23);7251-6
[PubMed:9393687] [WorldCat.org] [DOI] (P p)

M Bozzi, G Mignogna, S Stefanini, D Barra, C Longhi, P Valenti, E Chiancone
A novel non-heme iron-binding ferritin related to the DNA-binding proteins of the Dps family in Listeria innocua.
J. Biol. Chem.: 1997, 272(6);3259-65
[PubMed:9013563] [WorldCat.org] [DOI] (P p)