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  • Description: involved in 2,3-dihydroxybenzoate biosynthesis

Gene name dhbF
Essential no
Product unknown
Function biosynthesis of the siderophore bacillibactin
Gene expression levels in SubtiExpress: dhbF
MW, pI 263 kDa, 4.737
Gene length, protein length 7134 bp, 2378 aa
Immediate neighbours ybdZ, dhbB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DhbF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
DhbF expression.png

Categories containing this gene/protein

acquisition of iron, iron metabolism, membrane proteins, phosphoproteins

This gene is a member of the following regulons

AbrB regulon, Fur regulon

The gene

Basic information

  • Locus tag: BSU31960

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ATP-dependent AMP-binding enzyme family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylation on Ser-988 AND Ser-996 PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • the amount of the mRNA is substantially decreased upon depletion of RNase Y PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


Additional publications: PubMed

Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 81(6): 1459-1473.