DacF

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Gene name dacF
Synonyms
Essential no
Product penicillin-binding protein I,
D-alanyl-D-alanine carboxypeptidase
Function carboxypeptidase
Gene expression levels in SubtiExpress: dacF
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 43 kDa, 9.912
Gene length, protein length 1167 bp, 389 aa
Immediate neighbours spoIIAA, pupG
Sequences Protein DNA DNA_with_flanks
Genetic context
DacF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
DacF expression.png




























Categories containing this gene/protein

cell wall synthesis, sporulation proteins

This gene is a member of the following regulons

SigF regulon, SigG regulon, AbrB regulon

The gene

Basic information

  • Locus tag: BSU23480

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: modifies degree of cross-linking of glycan strands in peptidoglycan
  • Protein family: peptidase S11 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by casamino acids PubMed
    • expressed during sporulation in the forespore PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed