Cdd

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  • Description: cytidine deaminase

Gene name cdd
Synonyms
Essential no
Product cytidine deaminase
Function pyrimidine interconversion
Metabolic function and regulation of this protein in SubtiPathways:
Nucleoside catabolism, Nucleotides (regulation)
MW, pI 14 kDa, 4.7
Gene length, protein length 408 bp, 136 aa
Immediate neighbours era, dgkA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Cdd context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU25300

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Cytidine + H2O = uridine + NH3 (according to Swiss-Prot)
  • Protein family: cytidine and deoxycytidylate deaminase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 1JTK (complex with inhibitor), 1UWZ (with Arg56Ala substitution)
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

N Mejlhede, J F Atkins, J Neuhard
Ribosomal -1 frameshifting during decoding of Bacillus subtilis cdd occurs at the sequence CGA AAG.
J. Bacteriol.: 1999, 181(9);2930-7
[PubMed:10217788] [WorldCat.org] (P p)

B H Song, J Neuhard
Chromosomal location, cloning and nucleotide sequence of the Bacillus subtilis cdd gene encoding cytidine/deoxycytidine deaminase.
Mol. Gen. Genet.: 1989, 216(2-3);462-8
[PubMed:2526291] [WorldCat.org] [DOI] (P p)