Difference between revisions of "CdaS"

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(Biological materials)
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* '''Mutant:'''
 
* '''Mutant:'''
** GP983 (''[[yojJ]]''::''ermC''), available in [[Stülke]] lab  
+
** GP983 (''[[yojJ]]''::''ermC''), available in [[Jörg Stülke]]'s lab  
** GP1360 (''[[yojJ]]''::''spc''), available in [[Stülke]] lab
+
** GP1360 (''[[yojJ]]''::''spc''), available in [[Jörg Stülke]]'s lab
  
 
* '''Expression vector:'''
 
* '''Expression vector:'''

Revision as of 17:20, 30 October 2012

  • Description: maybe involved in the synthesis of c-di-AMP in vegetative cells

Gene name yojJ
Synonyms
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: yojJ
MW, pI 22 kDa, 5.367
Gene length, protein length 621 bp, 207 aa
Immediate neighbours yojK, yojI
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YojJ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YojJ expression.png















Categories containing this gene/protein

metabolism of signalling nucleotides

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU19430

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): YbbP

Extended information on the protein

  • Kinetic information:
  • Domains: contains a DAC domain potentially involved in the synthesis of c-di-AMP PubMed
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 2FB5 (the protein of B. cereus, 48% identity, 81% similarity)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Ute Römling
Great times for small molecules: c-di-AMP, a second messenger candidate in Bacteria and Archaea.
Sci Signal: 2008, 1(33);pe39
[PubMed:18714086] [WorldCat.org] [DOI] (I e)

Original publications

Yaara Oppenheimer-Shaanan, Ezequiel Wexselblatt, Jehoshua Katzhendler, Eylon Yavin, Sigal Ben-Yehuda
c-di-AMP reports DNA integrity during sporulation in Bacillus subtilis.
EMBO Rep.: 2011, 12(6);594-601
[PubMed:21566650] [WorldCat.org] [DOI] (I p)