Difference between revisions of "CcpC"

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(The protein)
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* '''Paralogous protein(s):'''
* '''Paralogous protein(s):'''
=== Genes controlled by CcpC ====
=== Extended information on the protein ===
=== Extended information on the protein ===

Revision as of 16:49, 9 February 2009

  • Description: write here

Gene name ccpC
Synonyms ykuM
Product transcriptional regulator (LysR family)
Function carbon catabolite and anaerobic repression of citB and citZ
MW, pI 33 kDa, 5.932
Gene length, protein length 879 bp, 293 aa
Immediate neighbours
Gene sequence (+200bp) Protein sequence
Genetic context
CcpC context.gif

The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Genes controlled by CcpC =


Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry:
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Linc Sonenshein, Tufts University, Boston, MA, USA Homepage

Your additional remarks


  1. Jourlin-Castelli C, Mani N, Nakano MM, Sonenshein AL (2000) CcpC, a novel regulator of the LysR family required for glucose repression of the citB gene in Bacillus subtilis. J Mol Biol 295:865-878. PubMed
  2. Kim, H. J., S. I. Kim, M. Ratnayake-Lecamwasam, K. Tachikawa, A. L. Sonenshein, and M. Strauch. (2003) Complex regulation of the Bacillus subtilis aconitase gene. J. Bacteriol. 185:1672-1680. PubMed
  3. Kim HJ, Jourlin-Castelli C, Kim SI, Sonenshein AL (2002a) Regulation of the Bacillus subtilis ccpC gene by CcpA and CcpC. Mol Microbiol 43:399-410. PubMed
  4. Kim SI, Jourlin-Castelli C, Wellington SR, Sonenshein AL (2003) Mechanism of repression by Bacillus subtilis CcpC, a LysR family regulator. J Mol Biol 334:609-624. PubMed
  5. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed