Difference between revisions of "BacF"

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** [[CodY]]: transcription repression {{PubMed|12372825}}
** [[CodY]]: transcription repression {{PubMed|12372825}}
** [[AbrB]]: transcription repression {{PubMed|12697329}}
** [[AbrB]]: transcription repression {{PubMed|12697329}}
** [[ScoC]]: transcription repression {{PubMed|19801406}}
* '''Additional information:'''  
* '''Additional information:'''  
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<pubmed> 12372825 12697329</pubmed>
<pubmed> 12372825 12697329 19801406</pubmed>
[[Category:Protein-coding genes]]
[[Category:Protein-coding genes]]

Revision as of 05:37, 7 October 2009

  • Description: aspartate aminotransferase involved in bacilysin synthesis

Gene name bacF
Synonyms ywfG, ipa-85d
Essential no
Product aspartate aminotransferase
Function biosynthesis of the antibiotic bacilysin
MW, pI 44 kDa, 5.347
Gene length, protein length 1197 bp, 399 aa
Immediate neighbours ywfH, bacE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YwfG context.gif
This image was kindly provided by SubtiList

The gene

Basic information

  • Locus tag: BSU37690

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: class-I pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


Takashi Inaoka, Guojun Wang, Kozo Ochi
ScoC regulates bacilysin production at the transcription level in Bacillus subtilis.
J Bacteriol: 2009, 191(23);7367-71
[PubMed:19801406] [WorldCat.org] [DOI] (I p)

Ayten Yazgan Karataş, Seçil Cetin, Gülay Ozcengiz
The effects of insertional mutations in comQ, comP, srfA, spo0H, spo0A and abrB genes on bacilysin biosynthesis in Bacillus subtilis.
Biochim Biophys Acta: 2003, 1626(1-3);51-6
[PubMed:12697329] [WorldCat.org] (P p)

Takashi Inaoka, Kosaku Takahashi, Mayumi Ohnishi-Kameyama, Mitsuru Yoshida, Kozo Ochi
Guanine nucleotides guanosine 5'-diphosphate 3'-diphosphate and GTP co-operatively regulate the production of an antibiotic bacilysin in Bacillus subtilis.
J Biol Chem: 2003, 278(4);2169-76
[PubMed:12372825] [WorldCat.org] [DOI] (P p)