ArsB

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  • Description: extrusion of arsenite

Gene name arsB
Synonyms yqcL
Essential no
Product arsenite exporter
Function detoxification of arsenate and arsenite
Gene expression levels in SubtiExpress: arsB
MW, pI 38 kDa, 9.773
Gene length, protein length 1038 bp, 346 aa
Immediate neighbours arsC, yqcK
Sequences Protein DNA DNA_with_flanks
Genetic context
ArsB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
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Categories containing this gene/protein

transporters/ other, resistance against toxic metals, Skin element

This gene is a member of the following regulons

ArsR regulon, SigF regulon

The gene

Basic information

  • Locus tag: BSU25790

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ACR3 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed early during sporulation in the forespore (SigF) PubMed
    • expressed in the presence of toxic metal ions (As(III), Cd(II) and Ag(I)) (ArsR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J. Mol. Biol.: 2006, 358(1);16-37
[PubMed:16497325] [WorldCat.org] [DOI] (P p)

T Sato, Y Kobayashi
The ars operon in the skin element of Bacillus subtilis confers resistance to arsenate and arsenite.
J. Bacteriol.: 1998, 180(7);1655-61
[PubMed:9537360] [WorldCat.org] [DOI] (P p)