Difference between revisions of "AroC"

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=The gene=
=The gene=

Revision as of 08:19, 23 June 2009

  • Description: 3-dehydroquinate dehydratase

Gene name aroC
Essential no
Product 3-dehydroquinate dehydratase
Function biosynthesis of aromatic amino acids
Metabolic function and regulation of this protein in SubtiPathways:
Phe, Tyr, Trp
MW, pI 27 kDa, 4.898
Gene length, protein length 765 bp, 255 aa
Immediate neighbours serA, rsiX
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AroC context.gif
This image was kindly provided by SubtiList

The gene

Basic information

  • Locus tag: BSU23080

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 3-dehydroquinate = 3-dehydroshikimate + H2O (according to Swiss-Prot)
  • Protein family: type-I 3-dehydroquinase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


R J Warburg, I Mahler, D J Tipper, H O Halvorson
Cloning the Bacillus subtilis 168 aroC gene encoding dehydroquinase.
Gene: 1984, 32(1-2);57-66
[PubMed:6442253] [WorldCat.org] [DOI] (P p)