Difference between revisions of "AroB"

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=The gene=
 
=The gene=

Revision as of 08:19, 23 June 2009

  • Description: 3-dehydroquinate synthase

Gene name aroB
Synonyms
Essential no
Product 3-dehydroquinate synthase
Function biosynthesis of aromatic amino acids
Metabolic function and regulation of this protein in SubtiPathways:
Phe, Tyr, Trp
MW, pI 40 kDa, 6.937
Gene length, protein length 1086 bp, 362 aa
Immediate neighbours aroH, aroF
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AroB context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU22700

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate (according to Swiss-Prot)
  • Protein family: class-I pyridine nucleotide-disulfide oxidoreductase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

J A Hoch, E W Nester
Gene-enzyme relationships of aromatic acid biosynthesis in Bacillus subtilis.
J. Bacteriol.: 1973, 116(1);59-66
[PubMed:4200844] [WorldCat.org] (P p)